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Cybin Inc. Common Stock

Cybin Inc., doing business as Helus Pharma, a clinical stage pharmaceutical company, focuses on developing therapies to treat various psychiatric and neurological conditions.It develops HLP003, a deuterated psilocybin analog, which is in phase 3 clinical trial to treat major depressive disorder (MDD); and HLP004, a deuterated N, N-dimethyltryptamine (DMT), which is in phase 2 clinical trial for treating generalized anxiety disorders. The company' preclinical product includes HLP005, a phenethylamine and tryptamine derivative to treat central nervous system. It has a strategic partnership agreement with Segal Trials to evaluating HLP003 for the adjunctive treatment of major depressive disorder; and with Osmind for mental health treatments. The company is headquartered in Toronto, Canada.

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Psychedelic Medicine

Canaccord Cuts Helus Pharma Price Target to $42, Maintains Buy Ahead of Phase 3 Trial Results

Canaccord analyst Sumant Kulkarni lowered the price target on Cybin D/B/A Helus Pharma to $42 from $45 while maintaining a Buy rating. The firm highlighted the lead candidate HLP003, a deuterated psilocin analog in a Phase 3 program for adjunctive treatment of major depressive disorder, with significant potential upside expected from the upcoming Phase 3 APPROACH trial results anticipated in the fourth quarter of 2026. Separately, on June 24, the company priced an underwritten public offering of 10,309,280 common shares at $4.85 each, generating approximately $50 million in gross proceeds to support ongoing operations and development programs.
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HELP

Helus Pharma Surpasses 86% Enrollment in Phase 3 Trial and Prices $50 Million Offering

Helus Pharma has surpassed 86% enrollment in its Phase 3 APPROACH trial for major depressive disorder and priced a US$50 million underwritten offering. The APPROACH study is evaluating HLP003, a novel serotonergic agonist that previously received Breakthrough Therapy Designation from the U.S. FDA, with topline data expected in the fourth quarter of 2026. The company priced 10,309,280 common shares at US$4.85 per share, with the offering expected to close on June 25, 2026, and proceeds will fund advancement of HLP003, the Phase 2 HLP004 program for generalized anxiety disorder, and the preclinical HLP005 candidate for treatment-resistant depression. Interim CEO Eric So stated the enrollment progress underscores execution of the clinical program. Helus Pharma is the commercial operating name of Cybin Inc.
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