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Assembly Biosciences Inc

Assembly Biosciences, Inc., a biotechnology company, develops therapeutic candidates for the treatment of viral diseases worldwide. Its pipeline includes long-acting helicase-primase inhibitors candidates, including ABI-5366 and ABI-1179, which are in Phase 1 clinical studies for recurrent genital herpes; and ABI-6250, an orally bioavailable hepatitis delta virus entry inhibitor that is in Phase 1a clinical study for the treatment of chronic hepatitis delta virus (HDV) infection. The company also develops ABI-4334, an orally bioavailable next generation capsid assembly modulator that is in Phase 1b study clinical trial for the treatment of chronic hepatitis B virus (HBV) infection; and ABI-7272, an oral broad-spectrum NNPI for the treatment of transplant-associated herpesviruses. It has an option, license, and collaboration agreement with Gilead Sciences, Inc. for the research and development of virology therapies. The company was formerly known as Ventrus Biosciences, Inc. and changed its name to Assembly Biosciences, Inc. in June 2014. Assembly Biosciences, Inc. was incorporated in 2005 and is headquartered in South San Francisco, California.

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Biotech & Genomic Medicine

Assembly Biosciences Reports Q2 2026 Results and Pipeline Updates

Assembly Biosciences reported second quarter 2026 financial results and announced expansion of ABI-6250 into cholestatic liver diseases including primary biliary cholangitis and primary sclerosing cholangitis. The company completed a $115 million gross financing and projects cash runway into 2029, including the first $75 million Gilead collaboration extension payment due in the fourth quarter of 2026. Gilead selected GS-1179, formerly ABI-1179, to advance in the HSV helicase primase inhibitor program with Phase 2 initiation expected by year-end 2026. Net loss attributable to common stockholders was $3.9 million, or $0.20 per share, compared to $10.2 million, or $1.33 per share, in the same period last year. Cash, cash equivalents and marketable securities totaled $320.4 million as of June 30, 2026.
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