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Chugai Pharmaceutical Co., Ltd.

Chugai Pharmaceutical Co., Ltd., together with its subsidiaries, engages in the research, development, manufacture, sale, importation, and exportation of pharmaceuticals in Japan and internationally. It offers oncology products, such as Alecensa, Avastin, FoundationOne, Herceptin, Kadcyla, Lunsumio, Perjeta, Phesgo, Polivy, and Tecentriq; Actemra for humanized anti-human IL-6 receptor monoclonal antibody; CellCept, an immunosuppressant; Enspryng, a pH-dependent binding humanized anti-IL-6 receptor monoclonal antibody; Evrysdi, a spinal muscular atrophy agent; Hemlibra, an anti-coagulation factor IXa/X humanized bispecific monoclonal antibody; Mircera, an erythropoiesis-stimulating agent; PiaSky, a pH-dependent binding humanized anti-complement (C5) monoclonal antibody; Tamiflu, an anti-influenza agent; and Vabysmo, an anti VEGF/anti Ang-2 bispecific antibody. The company was formerly known as Chugai Shinyaku Shokai and changed its name to Chugai Pharmaceutical Co., Ltd. in January 1943. The company was founded in 1925 and is headquartered in Chuo, Japan. Chugai Pharmaceutical Co., Ltd. operates as a subsidiary of Roche Holding AG.

Price · split & dividend adjusted
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4519.JP

Chugai Pharmaceutical shares fall as first-half operating profit rises 17% but full-year guidance is left unchanged

Chugai Pharmaceutical reported higher revenue and profit for the first half of the fiscal year ending December 2026, but its shares fell after the company left its full-year earnings forecast unchanged. Revenue rose 14.7% year on year to 663.3 billion yen, operating profit increased 16.9% to 319.6 billion yen, and interim profit grew 19.2% to 231.7 billion yen. In Japan, key products such as the ophthalmology drug Vabysmo drove growth, while overseas sales rose sharply on exports of Hemlibra to Roche and exports of an out-licensed dermatology drug. Other revenue, including royalty income, increased 44.5% to 96.8 billion yen. The stock briefly fell to the 6,800 yen level immediately after the earnings announcement, and on August 14 it closed at 6,933 yen, down about 3% from the previous day.
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4519.JP

Chugai Pharmaceutical's First-Half Net Profit Rises 19% to 231.7 Billion Yen, April–June Quarter Also Up 20%

Chugai Pharmaceutical reported consolidated net profit for the cumulative first half of the fiscal year ending December 2026 rose 19.2% year-on-year to 231.7 billion yen. For the April–June quarter, consolidated net profit increased 19.7% year-on-year to 116.3 billion yen, with the operating profit margin on sales unchanged from the previous year's 47.1% at 47.1%.
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4519.JP

Nikkei Average Plunges Sharply in Morning Session, Briefly Falls Over 3% on Middle East and Tariff Concerns

In the Tokyo stock market morning session, the Nikkei average plunged sharply, ending at 64,568.75 yen, down 2.79% from the previous business day. In addition to the previous day's decline in U.S. stocks, uncertainty over the Middle East situation and new tariffs set to be imposed by the Trump administration on the 24th weighed on sentiment, with the index briefly falling 3.14% to 64,334.29 yen. U.S. WTI crude oil futures traded in the 91-dollar range, and amid a global risk-off mood, the TOPIX ended the morning session down 1.01% at 4,012.79 points, while trading value on the Tokyo Stock Exchange Prime Market reached 4.336145 trillion yen. Among major stocks, SoftBank Group fell over 7% and Kioxia Holdings dropped over 9%, while Chugai Pharmaceutical rose over 3%. On the individual front, Disco, which announced earnings the previous day, topped the decliners list with a drop of over 14%, while KOA, which announced upward revisions and a dividend increase, surged over 10% to rank second on the gainers list.
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Longevity & Life Extension

Gero raises $17 million, bringing total equity funding to $34 million

Gero, a physics-first AI drug discovery company focused on aging, announced $17 million in new financing, bringing its total equity funding to $34 million. The company previously secured a collaboration with Chugai Pharmaceutical, a member of the Roche Group, which includes an upfront payment and up to $250 million in milestones plus royalties. Gero uses a physics-based framework and AI trained on approximately 10 million curated longitudinal medical records to identify therapeutic targets that slow aging and treat age-related diseases. The new funding will support preclinical development of its pipeline and expansion of pharmaceutical partnerships, with participation from Melnichek Investments and other investors from the AI and pharma sectors.
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